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KMID : 0367419960390030431
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Journal of Korean Pediatric Society
1996 Volume.39 No. 3 p.431 ~ p.435
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A Case of Hypothalamic Hamartoma with Gelastic Seizure Only
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Abstract
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Hypothalamic hamartoma is a congenital anomaly presenting precocious puberty, gelastic seizure and mental retardation. Other possible accompanying anomalies are cleft palate, tetralogy of Fallot, skeletal malformation and anal malformation. Bout
the
patient describing here manifested gelastic seizure only with isosignal mass of 1.5cm in diameter situated just behind optic chiasma in T1WI and T2WI of MRI. His EEG showed multifocal spike and sharp waves at left frontal and central area with
asymmetric sleep spindles. The seizure has been refractory to conventional antiepileptic drugs. He is now on Lamotrigine, a newly developed antiepileptic drug available.
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